Preheat oven to 350° Fahrenheit.
In a large bowl combine flour, dry milk, salt, garlic and onion powders, brown sugar and beef base.
Cut in bacon grease until mixture resembles cornmeal.
Add egg and just enough water to form a ball.
Flour counter top or work area.
Pat dough out over floured area until about 1 inch thick.
Take a rolling pin and roll out to about 1/2-inch thick.
Cut into bones or other shapes.
Place on a lightly greased baking sheet or pizza stone.
Bake 25 - 30 minutes.
Cool completely prior to giving to pups.
When completely cooled store in sealed container.